Advertisement
JOGC

Serum Hormonal Testing After Ovulation Triggering in Assisted Reproductive Technology: A Survey of Practice in Canadian In Vitro Fertilization Clinics

Published:November 18, 2022DOI:https://doi.org/10.1016/j.jogc.2022.11.001
      The rare occurrence of the failure to respond to ovulation trigger injection, leading to the lack of oocyte recovery at the time of retrieval, termed “empty follicle syndrome” (EFS), is a devastating event for both patient and clinician. The syndrome can be subclassified as false EFS (fEFS) and genuine EFS according to low versus normal post-trigger injection serum hormone levels, respectively.
      • Revelli A.
      • Carosso A.
      • Grassi G.
      • et al.
      Empty follicle syndrome revisited: definition, incidence, aetiology, early diagnosis and treatment.
      fEFS is most commonly due to human error in administration or pharmacologic failure, whereas genuine EFS is attributed to inherent pathophysiology, such as hormone receptor polymorphism or zona pellucida mutations.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Obstetrics and Gynaecology Canada
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Revelli A.
        • Carosso A.
        • Grassi G.
        • et al.
        Empty follicle syndrome revisited: definition, incidence, aetiology, early diagnosis and treatment.
        Reprod Biomed Online. 2017; 35: 132-138
        • Kummer N.E.
        • Feinn R.S.
        • Griffin D.W.
        • et al.
        Predicting successful induction of oocyte maturation after gonadotropin-releasing hormone agonist (GnRHa) trigger.
        Hum Reprod. 2013; 28: 152-159
        • Castillo J.C.
        • Juan G.V.
        • Humaidan P.
        Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS.
        J Assist Reprod Genet. 2012; 29: 249-253