Preeclampsia affects approximately 5% of pregnant women and is associated with serious
perinatal morbidity and mortality. Left untreated, and in its most serious forms,
preeclampsia leads to maternal vital organ damage, seizures, long-term cardiovascular
diseases, and potentially maternal death. Most of these adverse outcomes are associated
with maternal vascular malperfusion of the placenta, a disease that begins during
the first trimester when uteroplacental blood flow to the implantation site is increasing
exponentially. Because aspirin initiated in the first trimester of pregnancy has been
shown to improve placental perfusion and prevent preeclampsia, it is increasingly
used in various at-risk populations. However, care must be taken to respect the scientific
evidence regarding its optimal use.
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References
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Article Info
Publication History
Published online: August 02, 2022
Footnotes
Disclosures: The authors declare they have nothing to disclose.
Each author has indicated they meet the journal’s requirements for authorship.
Identification
Copyright
© 2022 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.
