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Endometrial Biopsy in Low-Risk Women: Are We Over-Investigating?

      Abstract

      The appropriate age at which to perform endometrial biopsy for abnormal uterine bleeding (AUB) is controversial. This study aimed to determine the prevalence of malignant and premalignant pathologies in women aged 41–49 years with AUB and without risk factors for endometrial cancer. Records of women who had undergone a biopsy at the gynaecology clinic of the Centre hospitalier de l'Université de Montréal between 2014 and 2018 were reviewed. Of the 209 women included in the study, 2 had atypical hyperplasia, which resolved without treatment, and 3 had hyperplasia without atypia. The remaining women had benign results, showing that the prevalence of malignant and premalignant endometrial pathologies is low in this subgroup of patients.

      Résumé

      L’âge auquel il convient de réaliser une biopsie de l’endomètre en raison de saignements utérins anormaux (SUA) est controversé. Cette étude visait à déterminer la prévalence des pathologies malignes et prémalignes chez les femmes de 41 à 49 ans atteintes de SUA n’ayant aucun facteur de risque pour le cancer de l’endomètre. Les dossiers des femmes ayant subi une biopsie entre 2014 et 2018 à la clinique de gynécologie du Centre hospitalier de l’Université de Montréal ont été examinés. Des 209 femmes incluses dans l’étude, 2 avaient une hyperplasie atypique, qui s’est résorbée sans traitement, et 3 présentaient une hyperplasie sans atypie. Chez les autres femmes, les résultats se sont révélés bénins, ce qui montre que la prévalence des pathologies endométriales malignes et prémalignes est faible dans ce sous-groupe de patientes.

      Keywords

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