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Sexual and Psychosocial Outcome After Neovaginoplasty Using Interceed in Females with Mayer-Rokitansky-Küster-Hauser Syndrome: A Case-Control Study

Published:April 26, 2022DOI:https://doi.org/10.1016/j.jogc.2022.03.018

      Abstract

      There is a paucity of research on psychosexual outcomes after neo-vaginoplasty in women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. We compared anatomical and psychosexual outcomes between women with MRKH syndrome who had undergone vaginoplasty and age-matched, sexually active, childless women. Outcomes were assessed using the female sexual function index (FSFI), World Health Organization Disability Assessment Schedule (WHODAS 2.0), General Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire (PHQ-9) tools. Although mean vaginal length was shorter in women with MRKH syndrome than controls (8.6 ± 1.8 cm vs 9.3 ± 2.6 cm), FSFI scores were comparable in both groups (27.8 ± 1.4 vs. 27.3 ± 4.1). Women with MRKH syndrome reported fewer depressive symptoms, and WHODAS 2.0 scores were comparable in both groups (8.9 ± 2.4 vs. 7.8 ± 6.7). Therefore, psychosexual outcomes for women who had undergone neo-vaginoplasty for MRKH syndrome were not different from those of the general population.

      Résumé

      On accuse un manque d’études sur le devenir psychosexuel à la suite d’une vaginoplastie chez les femmes atteintes du syndrome de Mayer-Rokitansky-Küster-Hauser (MRKH). Nous avons comparé le devenir anatomique et psychosexuel entre les femmes atteintes du syndrome de MRKH ayant subi une vaginoplastie et les femmes du même âge étant sexuellement actives et sans enfants. Le devenir a été évalué au moyen de l’indice de fonction sexuelle féminine (FSFI), de l’instrument d’évaluation du handicap de l’Organisation mondiale de la Santé (WHODAS 2.0), du questionnaire sur le trouble anxieux généralisé GAD-7 et du questionnaire sur la santé du patient (PHQ-9). Bien que la longueur vaginale moyenne était plus courte chez les femmes atteintes du syndrome de MRKH que dans le groupe témoin (8,6 ± 1,8 cm p/r à 9,3 ± 2,6 cm), les scores de FSFI étaient comparables (27,8 ± 1,4 p/r à 27,3 ± 4,1). Les femmes atteintes du syndrome de MRKH ont signalé moins de symptômes dépressifs et les scores du WHODAS 2.0 étaient comparables entre les deux groupes (8,9 ± 2,4 p/r à 7,8 ± 6,7). Par conséquent, le devenir psychosexuel chez les femmes ayant subi une vaginoplastie en raison du syndrome de MRKH n’était pas différent de celui dans la population générale.

      Keywords

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