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Review • Revue| Volume 44, ISSUE 3, P286-293.e3, March 2022

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A Systematic Review of the Cost of Chronic Pelvic Pain in Women

Published:September 25, 2021DOI:https://doi.org/10.1016/j.jogc.2021.08.011

      ABSTRACT

      Objective

      To systematically summarize the evidence on costs related to chronic pelvic pain (CPP) for women.

      Data sources

      Electronic databases (MEDLINE, EMBASE, PubMed, and Cochrane Library) were searched for English and French articles published from 1990 to January 2021

      Study selection

      Of 1304 articles screened, 67 were screened in full-text form, and a total of 13 articles were included in the final analysis. Articles included involved cost studies that estimated hospital or health system costs for pelvic pain, dysmenorrhea, dyspareunia, endometriosis with pain, interstitial cystitis, or painful bladder syndrome.

      Data extraction and synthesis

      A standardized form was created to extract study setting, design, and population; patient demographics; study duration; and reported costs of CPP components and amounts. Two independent reviewers completed the data extraction, and discrepancies were resolved through discussion with a third reviewer.

      Conclusion

      Estimated health care costs ranged from US$1367 to US$7043 per woman per year. Prescription costs ranged from US$193 to US$2457 per woman per year. Indirect costs ranged from US$4216 to US$12 789 per woman per year. Combined costs ranged from US$1820 to US$20 898 per woman per year. The yearly costs of CPP varied according to country; yearly costs were estimated to be $2.8 billion, ¥191,680 to ¥246,488, and $16 970 to $20 898 per woman per year in the United Sates, Japan, and Australia, respectively. The literature suggests that CPP represents a considerable economic burden on women and health care systems internationally, with indirect costs contributing a significant portion of total costs.

      RÉSUMÉ

      Objectif

      Faire une revue systématique des données probantes sur les coûts liés à la douleur pelvienne chronique (DPC) chez les femmes.

      Sources de données

      Des recherches ont été effectuées dans les bases de données électroniques Medline, Embase, PubMed et Cochrane Library pour trouver des articles publiés en anglais ou en français entre 1990 et janvier 2021.

      Sélection des études

      Des 1 304 articles recensés, 67 ont été examinés dans leur version intégrale, et 13 ont été inclus dans l'analyse finale. Ces articles présentaient des études des coûts estimés pour l'hospitalisation ou pour le système de santé en ce qui concerne la douleur pelvienne, la dysménorrhée, la dyspareunie, l'endométriose avec douleur ou la cystite interstitielle (syndrome de la vessie douloureuse).

      Extraction et synthèse des données

      Un formulaire normalisé a été créé pour extraire le contexte, la méthodologie et la population de l’étude; les caractéristiques démographiques des patientes; la durée de l’étude; et les coûts déclarés des composantes de la DPC et les totaux. Deux évaluateurs indépendants ont extrait les données, et les divergences ont été résolues par une discussion avec un troisième évaluateur.

      Conclusion

      Les coûts estimés pour le système de santé variaient de 1 367 à 7 043 $ US par femme par année; le coût des ordonnances, de 193 à 2 457 $ US par femme par année; les coûts indirects, de 4 216 à 12 789 $ US par femme par année; et les coûts combinés, de 1 820 à 20 898 $ US par femme par année. Les coûts annuels estimés de la DPC par femme par année variaient d'un pays à l'autre, soit 2,8 G$ aux États-Unis, entre 191 680 et 246 488 ¥ au Japon et entre 16 970 et 20 898 $ en Australie. La littérature laisse entendre que la DPC représente un fardeau économique considérable pour les femmes et les systèmes de santé partout dans le monde, les coûts indirects constituant une part importante des coûts totaux.

      Keywords

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