A 68-year-old woman was referred to gynaecologic oncology for a large, slow-growing vulvar mass. She was asymptomatic but found its size cumbersome. History included remote total hysterectomy and bilateral salpingo-oophorectomy for menorrhagia. Ultrasound demonstrated a well-circumscribed solid vascular mass. On examination, the mass had prominent vasculature and occupied the right labium majus, but was free of underlying tissue (Figure). There was no inguinal lymphadenopathy.
Computed tomography described the mass extending inferiorly from near the vagina, measuring 9.3 x 6.9 x 7.0 cm. Density was similar to muscle with internal vascularity. There was no evidence of metastatic disease. Right radical vulvectomy was completed. Pathology demonstrated benign leiomyoma, positive for estrogen receptor, progesterone receptor, desmin, smooth muscle actin, and CD10, and negative for CD34 and S100. Vulvar leiomyoma is exceptionally rare but should be considered in the differential diagnosis of a vulvar mass.
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, - Zhao T
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Myxoid epithelial leiomyoma of the vulva: a case report and literature review.
Case Reports in Obstetrics and Gynecology. 2015; 2015 (Available at:)894830https://doi.org/10.1155/2015/894830
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Consent: Consent to publish these images was obtained from the patient.
References
- Review of the pathophysiology, diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor.The Journal of International Medical Research. 2017; 46 (Available at:): 663-674
- Myxoid epithelial leiomyoma of the vulva: a case report and literature review.Case Reports in Obstetrics and Gynecology. 2015; 2015 (Available at:)894830https://doi.org/10.1155/2015/894830
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Published online: June 28, 2021
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© 2020 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.
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- Léiomyome volumineux bénin de la vulve : une localisation extra-utérine insoliteJournal of Obstetrics and Gynaecology Canada Vol. 44Issue 3
- PreviewUne femme de 68 ans a été orientée vers la gynécologie oncologique en raison d'une masse vulvaire volumineuse à croissance lente. Elle ne présentait aucun symptôme, mais la masse la gênait. Elle avait déjà subi une hystérectomie totale et une salpingoovariectomie bilatérale en raison de ménorragies. L'examen échographique a révélé la présence d'une masse solide vascularisée bien circonscrite. À l'examen, la masse avait un important système vasculaire et se situait dans la grande lèvre droite, mais ne présentait aucun tissu sous-jacent (figure).
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